Analgesic, antiallodynic, and anticonvulsant activity of novel hybrid molecules derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide in animal models of pain and epilepsy

The purpose of the present study was to examine the analgesic activity of six novel hybrid molecules, which demonstrated in the previous research anticonvulsant activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure (scPTZ) tests in mice. The antinociceptive p...

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Detalles Bibliográficos
Autores principales: Rapacz, Anna, Kamiński, Krzysztof, Obniska, Jolanta, Koczurkiewicz, Paulina, Pękala, Elżbieta, Filipek, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411412/
https://www.ncbi.nlm.nih.gov/pubmed/28188357
http://dx.doi.org/10.1007/s00210-017-1358-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411412/
https://www.ncbi.nlm.nih.gov/pubmed/28188357
http://dx.doi.org/10.1007/s00210-017-1358-3

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