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Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

Protein homeostasis (proteostasis), the correct balance between production and degradation of proteins, is essential for the health and survival of cells. Proteostasis requires an intricate network of protein quality control pathways (the proteostasis network) that work to prevent protein aggregatio...

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Detalles Bibliográficos
Autores principales: Webster, Christopher P., Smith, Emma F., Shaw, Pamela J., De Vos, Kurt J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411428/
https://www.ncbi.nlm.nih.gov/pubmed/28512398
http://dx.doi.org/10.3389/fnmol.2017.00123