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Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?
Protein homeostasis (proteostasis), the correct balance between production and degradation of proteins, is essential for the health and survival of cells. Proteostasis requires an intricate network of protein quality control pathways (the proteostasis network) that work to prevent protein aggregatio...
Autores principales: | Webster, Christopher P., Smith, Emma F., Shaw, Pamela J., De Vos, Kurt J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411428/ https://www.ncbi.nlm.nih.gov/pubmed/28512398 http://dx.doi.org/10.3389/fnmol.2017.00123 |
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