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The concordance between the volume hotspot and the grade hotspot: a 3-D reconstructive model using the pathology outputs from the PROMIS trial

OBJECTIVES: The rationale for directing targeted biopsy towards the centre of lesions has been questioned in light of prostate cancer grade heterogeneity. In this study, we assess the assumption that the maximum cancer Gleason grade (Gleason grade hotspot) lies within the maximum dimension (volume h...

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Detalles Bibliográficos
Autores principales: El-Shater Bosaily, A, Valerio, M, Hu, Y, Freeman, A, Jameson, C, Brown, L, Kaplan, R, Hindley, R G, Barratt, D, Emberton, M, Ahmed, H U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411671/
https://www.ncbi.nlm.nih.gov/pubmed/27401032
http://dx.doi.org/10.1038/pcan.2016.7