Whole-genome sequencing identifies homozygous BRCA2 deletion guiding treatment in dedifferentiated prostate cancer

Whole-genome sequencing (WGS) has transformed the understanding of the genetic drivers of cancer and is increasingly being used in cancer medicine to identify personalized therapies. Here we describe a case in which the application of WGS identified a tumoral BRCA2 deletion in a patient with aggress...

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Detalles Bibliográficos
Autores principales: Purshouse, Karin, Schuh, Anna, Fairfax, Benjamin P., Knight, Sam, Antoniou, Pavlos, Dreau, Helene, Popitsch, Niko, Gatter, Kevin, Roberts, Ian, Browning, Lisa, Traill, Zoe, Kerr, David, Verrill, Clare, Tuthill, Mark, Taylor, Jenny C., Protheroe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411692/
https://www.ncbi.nlm.nih.gov/pubmed/28487881
http://dx.doi.org/10.1101/mcs.a001362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411692/
https://www.ncbi.nlm.nih.gov/pubmed/28487881
http://dx.doi.org/10.1101/mcs.a001362

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