Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma

Cushing's disease (CD) is caused by pituitary corticotroph adenomas that secrete excess adrenocorticotropic hormone (ACTH). In these tumors, somatic mutations in the gene USP8 have been identified as recurrent and pathogenic and are the sole known molecular driver for CD. Although other somatic...

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Detalles Bibliográficos
Autores principales: Uzilov, Andrew V., Cheesman, Khadeen C., Fink, Marc Y., Newman, Leah C., Pandya, Chetanya, Lalazar, Yelena, Hefti, Marco, Fowkes, Mary, Deikus, Gintaras, Lau, Chun Yee, Moe, Aye S., Kinoshita, Yayoi, Kasai, Yumi, Zweig, Micol, Gupta, Arpeta, Starcevic, Daniela, Mahajan, Milind, Schadt, Eric E., Post, Kalmon D., Donovan, Michael J., Sebra, Robert, Chen, Rong, Geer, Eliza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411693/
https://www.ncbi.nlm.nih.gov/pubmed/28487882
http://dx.doi.org/10.1101/mcs.a001602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411693/
https://www.ncbi.nlm.nih.gov/pubmed/28487882
http://dx.doi.org/10.1101/mcs.a001602

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