Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1–3 family

MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression critical for organismal viability. Changes in miRNA activity are common in cancer, but how these changes relate to subsequent alterations in transcription and the process of tumorigenesis is not well understood. Here, we repor...

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Detalles Bibliográficos
Autores principales: JnBaptiste, Courtney K., Gurtan, Allan M., Thai, Kevin K., Lu, Victoria, Bhutkar, Arjun, Su, Mei-Ju, Rotem, Asaf, Jacks, Tyler, Sharp, Phillip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411708/
https://www.ncbi.nlm.nih.gov/pubmed/28446596
http://dx.doi.org/10.1101/gad.296301.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411708/
https://www.ncbi.nlm.nih.gov/pubmed/28446596
http://dx.doi.org/10.1101/gad.296301.117

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