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The histone variant H2A.Z promotes splicing of weak introns

Multiple lines of evidence implicate chromatin in the regulation of premessenger RNA (pre-mRNA) splicing. However, the influence of chromatin factors on cotranscriptional splice site usage remains unclear. Here we investigated the function of the highly conserved histone variant H2A.Z in pre-mRNA sp...

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Detalles Bibliográficos
Autores principales: Nissen, Kelly E., Homer, Christina M., Ryan, Colm J., Shales, Michael, Krogan, Nevan J., Patrick, Kristin L., Guthrie, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411709/
https://www.ncbi.nlm.nih.gov/pubmed/28446597
http://dx.doi.org/10.1101/gad.295287.116