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Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation
Vascular disease progression is associated with marked changes in vascular smooth muscle cell (SMC) phenotype and function. SMC contractile gene expression and, thus differentiation, is under direct transcriptional control by the transcription factor, serum response factor (SRF); however, the mechan...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411712/ https://www.ncbi.nlm.nih.gov/pubmed/26940659 http://dx.doi.org/10.1038/ncomms10830 |