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Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation

Vascular disease progression is associated with marked changes in vascular smooth muscle cell (SMC) phenotype and function. SMC contractile gene expression and, thus differentiation, is under direct transcriptional control by the transcription factor, serum response factor (SRF); however, the mechan...

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Detalles Bibliográficos
Autores principales: Horita, Henrick, Wysoczynski, Christina L., Walker, Lori A., Moulton, Karen S., Li, Marcella, Ostriker, Allison, Tucker, Rebecca, McKinsey, Timothy A., Churchill, Mair E. A., Nemenoff, Raphael A., Weiser-Evans, Mary C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411712/
https://www.ncbi.nlm.nih.gov/pubmed/26940659
http://dx.doi.org/10.1038/ncomms10830