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Adaptive evolution of complex innovations through stepwise metabolic niche expansion

A central challenge in evolutionary biology concerns the mechanisms by which complex metabolic innovations requiring multiple mutations arise. Here, we propose that metabolic innovations accessible through the addition of a single reaction serve as stepping stones towards the later establishment of...

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Detalles Bibliográficos
Autores principales: Szappanos, Balázs, Fritzemeier, Jonathan, Csörgő, Bálint, Lázár, Viktória, Lu, Xiaowen, Fekete, Gergely, Bálint, Balázs, Herczeg, Róbert, Nagy, István, Notebaart, Richard A., Lercher, Martin J., Pál, Csaba, Papp, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411730/
https://www.ncbi.nlm.nih.gov/pubmed/27197754
http://dx.doi.org/10.1038/ncomms11607