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Genome graphs and the evolution of genome inference

The human reference genome is part of the foundation of modern human biology and a monumental scientific achievement. However, because it excludes a great deal of common human variation, it introduces a pervasive reference bias into the field of human genomics. To reduce this bias, it makes sense to...

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Detalles Bibliográficos
Autores principales: Paten, Benedict, Novak, Adam M., Eizenga, Jordan M., Garrison, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411762/
https://www.ncbi.nlm.nih.gov/pubmed/28360232
http://dx.doi.org/10.1101/gr.214155.116