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Combination of short-read, long-read, and optical mapping assemblies reveals large-scale tandem repeat arrays with population genetic implications

Accurate and contiguous genome assembly is key to a comprehensive understanding of the processes shaping genomic diversity and evolution. Yet, it is frequently constrained by constitutive heterochromatin, usually characterized by highly repetitive DNA. As a key feature of genome architecture associa...

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Detalles Bibliográficos
Autores principales: Weissensteiner, Matthias H., Pang, Andy W.C., Bunikis, Ignas, Höijer, Ida, Vinnere-Petterson, Olga, Suh, Alexander, Wolf, Jochen B.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411765/
https://www.ncbi.nlm.nih.gov/pubmed/28360231
http://dx.doi.org/10.1101/gr.215095.116