Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation

Long-read single-molecule sequencing has revolutionized de novo genome assembly and enabled the automated reconstruction of reference-quality genomes. However, given the relatively high error rates of such technologies, efficient and accurate assembly of large repeats and closely related haplotypes...

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Detalles Bibliográficos
Autores principales: Koren, Sergey, Walenz, Brian P., Berlin, Konstantin, Miller, Jason R., Bergman, Nicholas H., Phillippy, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411767/
https://www.ncbi.nlm.nih.gov/pubmed/28298431
http://dx.doi.org/10.1101/gr.215087.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411767/
https://www.ncbi.nlm.nih.gov/pubmed/28298431
http://dx.doi.org/10.1101/gr.215087.116

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