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Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation
Long-read single-molecule sequencing has revolutionized de novo genome assembly and enabled the automated reconstruction of reference-quality genomes. However, given the relatively high error rates of such technologies, efficient and accurate assembly of large repeats and closely related haplotypes...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411767/ https://www.ncbi.nlm.nih.gov/pubmed/28298431 http://dx.doi.org/10.1101/gr.215087.116 |