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Fast and accurate de novo genome assembly from long uncorrected reads

The assembly of long reads from Pacific Biosciences and Oxford Nanopore Technologies typically requires resource-intensive error-correction and consensus-generation steps to obtain high-quality assemblies. We show that the error-correction step can be omitted and that high-quality consensus sequence...

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Detalles Bibliográficos
Autores principales: Vaser, Robert, Sović, Ivan, Nagarajan, Niranjan, Šikić, Mile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411768/
https://www.ncbi.nlm.nih.gov/pubmed/28100585
http://dx.doi.org/10.1101/gr.214270.116