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HINGE: long-read assembly achieves optimal repeat resolution

Long-read sequencing technologies have the potential to produce gold-standard de novo genome assemblies, but fully exploiting error-prone reads to resolve repeats remains a challenge. Aggressive approaches to repeat resolution often produce misassemblies, and conservative approaches lead to unnecess...

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Detalles Bibliográficos
Autores principales: Kamath, Govinda M., Shomorony, Ilan, Xia, Fei, Courtade, Thomas A., Tse, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411769/
https://www.ncbi.nlm.nih.gov/pubmed/28320918
http://dx.doi.org/10.1101/gr.216465.116