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Hybrid assembly of the large and highly repetitive genome of Aegilops tauschii, a progenitor of bread wheat, with the MaSuRCA mega-reads algorithm

Long sequencing reads generated by single-molecule sequencing technology offer the possibility of dramatically improving the contiguity of genome assemblies. The biggest challenge today is that long reads have relatively high error rates, currently around 15%. The high error rates make it difficult...

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Detalles Bibliográficos
Autores principales: Zimin, Aleksey V., Puiu, Daniela, Luo, Ming-Cheng, Zhu, Tingting, Koren, Sergey, Marçais, Guillaume, Yorke, James A., Dvořák, Jan, Salzberg, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411773/
https://www.ncbi.nlm.nih.gov/pubmed/28130360
http://dx.doi.org/10.1101/gr.213405.116