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Hybrid assembly of the large and highly repetitive genome of Aegilops tauschii, a progenitor of bread wheat, with the MaSuRCA mega-reads algorithm
Long sequencing reads generated by single-molecule sequencing technology offer the possibility of dramatically improving the contiguity of genome assemblies. The biggest challenge today is that long reads have relatively high error rates, currently around 15%. The high error rates make it difficult...
Autores principales: | Zimin, Aleksey V., Puiu, Daniela, Luo, Ming-Cheng, Zhu, Tingting, Koren, Sergey, Marçais, Guillaume, Yorke, James A., Dvořák, Jan, Salzberg, Steven L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411773/ https://www.ncbi.nlm.nih.gov/pubmed/28130360 http://dx.doi.org/10.1101/gr.213405.116 |
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