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Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set

Most recent initiatives to sequence and assemble new species’ genomes de novo fail to achieve the ultimate endpoint to produce contigs, each representing one whole chromosome. Even the best-assembled genomes (using contemporary technologies) consist of subchromosomal-sized scaffolds. To circumvent t...

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Detalles Bibliográficos
Autores principales: Damas, Joana, O'Connor, Rebecca, Farré, Marta, Lenis, Vasileios Panagiotis E., Martell, Henry J., Mandawala, Anjali, Fowler, Katie, Joseph, Sunitha, Swain, Martin T., Griffin, Darren K., Larkin, Denis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411781/
https://www.ncbi.nlm.nih.gov/pubmed/27903645
http://dx.doi.org/10.1101/gr.213660.116