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Mechanisms underlying the pathogenesis of hyper-contractility of bronchial smooth muscle in allergic asthma

Airway hyperresponsiveness (AHR) and inflammation are key pathophysiological features of asthma. Enhanced contraction of bronchial smooth muscle (BSM) is one of the causes of the AHR. It is thus important for development of asthma therapy to understand the change in the contractile signaling of airw...

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Detalles Bibliográficos
Autores principales: Sakai, Hiroyasu, Suto, Wataru, Kai, Yuki, Chiba, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Society of Smooth Muscle Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411784/
https://www.ncbi.nlm.nih.gov/pubmed/28484126
http://dx.doi.org/10.1540/jsmr.53.37