Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2

[Image: see text] 17β-Hydroxysteroid dehydrogenase type 2 (17β-HSD2) converts the active steroid hormones estradiol, testosterone, and 5α-dihydrotestosterone into their weakly active forms estrone, Δ(4)-androstene-3,17-dione, and 5α-androstane-3,17-dione, respectively, thereby regulating cell- and t...

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Detalles Bibliográficos
Autores principales: Vuorinen, Anna, Engeli, Roger T., Leugger, Susanne, Bachmann, Fabio, Akram, Muhammad, Atanasov, Atanas G., Waltenberger, Birgit, Temml, Veronika, Stuppner, Hermann, Krenn, Liselotte, Ateba, Sylvin B., Njamen, Dieudonné, Davis, Rohan A., Odermatt, Alex, Schuster, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411959/
https://www.ncbi.nlm.nih.gov/pubmed/28319389
http://dx.doi.org/10.1021/acs.jnatprod.6b00950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411959/
https://www.ncbi.nlm.nih.gov/pubmed/28319389
http://dx.doi.org/10.1021/acs.jnatprod.6b00950

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