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The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro

BACKGROUND: The use of fetal bovine serum (FBS) as a media supplement for the ex vivo expansion of bone-marrow derived mesenchymal stromal cells (BM-MSC) has been discouraged by regulatory agencies, due to the risk of transmitting zoonoses and to elicit immune reactions in the host once transplanted...

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Detalles Bibliográficos
Autores principales: Bernardi, Martina, Agostini, Francesco, Chieregato, Katia, Amati, Eliana, Durante, Cristina, Rassu, Mario, Ruggeri, Marco, Sella, Sabrina, Lombardi, Elisabetta, Mazzucato, Mario, Astori, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412035/
https://www.ncbi.nlm.nih.gov/pubmed/28460641
http://dx.doi.org/10.1186/s12967-017-1185-9