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The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro
BACKGROUND: The use of fetal bovine serum (FBS) as a media supplement for the ex vivo expansion of bone-marrow derived mesenchymal stromal cells (BM-MSC) has been discouraged by regulatory agencies, due to the risk of transmitting zoonoses and to elicit immune reactions in the host once transplanted...
Autores principales: | Bernardi, Martina, Agostini, Francesco, Chieregato, Katia, Amati, Eliana, Durante, Cristina, Rassu, Mario, Ruggeri, Marco, Sella, Sabrina, Lombardi, Elisabetta, Mazzucato, Mario, Astori, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412035/ https://www.ncbi.nlm.nih.gov/pubmed/28460641 http://dx.doi.org/10.1186/s12967-017-1185-9 |
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