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Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases

BACKGROUND: Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status in breast cancer (BC) patients. Real-time quantitative polymerase-chain-reaction (qRT-PCR) is able to detect HER2 overexpression....

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Detalles Bibliográficos
Autores principales: Zoppoli, Gabriele, Garuti, Anna, Cirmena, Gabriella, di Cantogno, Ludovica Verdun, Botta, Cristina, Gallo, Maurizio, Ferraioli, Domenico, Carminati, Enrico, Baccini, Paola, Curto, Monica, Fregatti, Piero, Isnaldi, Edoardo, Lia, Michela, Murialdo, Roberto, Friedman, Daniele, Sapino, Anna, Ballestrero, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412048/
https://www.ncbi.nlm.nih.gov/pubmed/28460632
http://dx.doi.org/10.1186/s12967-017-1195-7