Glycyrrhizin Protects Rats from Sepsis by Blocking HMGB1 Signaling

Background. HMGB1 acts as an important inflammatory mediator and is a potential therapeutic target for sepsis. Glycyrrhizin (GL), a natural triterpene glycoside derived from licorice, has been demonstrated to inhibit HMGB1 activity. The aim of this study is to explore how GL affects the HMGB1 signal...

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Detalles Bibliográficos
Autores principales: Zhao, Feng, Fang, Yong, Deng, Shuixiang, Li, Xiantao, Zhou, Yun, Gong, Ye, Zhu, Hechen, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412259/
https://www.ncbi.nlm.nih.gov/pubmed/28484719
http://dx.doi.org/10.1155/2017/9719647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412259/
https://www.ncbi.nlm.nih.gov/pubmed/28484719
http://dx.doi.org/10.1155/2017/9719647

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