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Endogenously Expressed IL-4Rα Promotes the Malignant Phenotype of Human Pancreatic Cancer In Vitro and In Vivo

Exogenous interleukin-4 (IL-4) has been demonstrated to affect the growth of different human malignancies including pancreatic cancer cells. The aim of our study was to determine the role of endogenously expressed IL-4-receptor-α-chain (IL-4Rα) in pancreatic cancer cells. IL-4Rα-suppression was achi...

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Detalles Bibliográficos
Autores principales: Traub, Benno, Sun, Lie, Ma, Yongsu, Xu, Pengfei, Lemke, Johannes, Paschke, Stephan, Henne-Bruns, Doris, Knippschild, Uwe, Kornmann, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412302/
https://www.ncbi.nlm.nih.gov/pubmed/28350325
http://dx.doi.org/10.3390/ijms18040716