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Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer

Genetic polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) enzyme may influence DNA methylation. Alterations in DNA methylation patterns of genes involved in the regulation of the cell cycle, DNA repair, cell adherence and metastasis process are known to contribute to cancer developmen...

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Detalles Bibliográficos
Autores principales: Ferlazzo, Nadia, Currò, Monica, Zinellu, Angelo, Caccamo, Daniela, Isola, Gaetano, Ventura, Valeria, Carru, Ciriaco, Matarese, Giovanni, Ientile, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412310/
https://www.ncbi.nlm.nih.gov/pubmed/28353639
http://dx.doi.org/10.3390/ijms18040724