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Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer
Genetic polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) enzyme may influence DNA methylation. Alterations in DNA methylation patterns of genes involved in the regulation of the cell cycle, DNA repair, cell adherence and metastasis process are known to contribute to cancer developmen...
Autores principales: | Ferlazzo, Nadia, Currò, Monica, Zinellu, Angelo, Caccamo, Daniela, Isola, Gaetano, Ventura, Valeria, Carru, Ciriaco, Matarese, Giovanni, Ientile, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412310/ https://www.ncbi.nlm.nih.gov/pubmed/28353639 http://dx.doi.org/10.3390/ijms18040724 |
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