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Inhibition or Stimulation of Autophagy Affects Early Formation of Lipofuscin-Like Autofluorescence in the Retinal Pigment Epithelium Cell

The accumulation of lipofuscin in the retinal pigment epithelium (RPE) is dependent on the effectiveness of photoreceptor outer segment material degradation. This study explored the role of autophagy in the fate of RPE lipofuscin degradation. After seven days of feeding with either native or modifie...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Tzekov, Radouil, Li, Huapeng, McDowell, J. Hugh, Gao, Guangping, Smith, W. Clay, Tang, Shibo, Kaushal, Shalesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412314/
https://www.ncbi.nlm.nih.gov/pubmed/28353645
http://dx.doi.org/10.3390/ijms18040728