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Classical and Novel TSPO Ligands for the Mitochondrial TSPO Can Modulate Nuclear Gene Expression: Implications for Mitochondrial Retrograde Signaling

It is known that knockdown of the mitochondrial 18 kDa translocator protein (TSPO) as well as TSPO ligands modulate various functions, including functions related to cancer. To study the ability of TSPO to regulate gene expression regarding such functions, we applied microarray analysis of gene expr...

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Detalles Bibliográficos
Autores principales: Yasin, Nasra, Veenman, Leo, Singh, Sukhdev, Azrad, Maya, Bode, Julia, Vainshtein, Alex, Caballero, Beatriz, Marek, Ilan, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412370/
https://www.ncbi.nlm.nih.gov/pubmed/28387723
http://dx.doi.org/10.3390/ijms18040786