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Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

Ghrelin, an orexigenic hormone released primarily from the gut, signals the hypothalamus to stimulate growth hormone release, enhance appetite and promote weight gain. The ghrelin receptor, aka Growth Hormone Secretagogue Receptor (GHS-R), is highly expressed in the brain, with highest expression in...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Shan, Bongmba, Odelia Y. N., Yue, Jing, Lee, Jong Han, Lin, Ligen, Saito, Kenji, Pradhan, Geetali, Li, De-Pei, Pan, Hui-Lin, Xu, Allison, Guo, Shaodong, Xu, Yong, Sun, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412416/
https://www.ncbi.nlm.nih.gov/pubmed/28420089
http://dx.doi.org/10.3390/ijms18040832