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SAK-HV Decreases the Self-Ubiquitination of MEKK1 to Promote Macrophage Proliferation via MAPK/ERK and JNK Pathways

SAK-HV is an anti-atherosclerosis recombinant fusion protein developed by our lab. Our study determined that SAK-HV promoted macrophage proliferation, of which the mechanism was explored by both RAW264.7 cells and primary macrophages. Mass spectrometric analysis and co-immunoprecipitation were combi...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Chen, Yao, Gan, Xiangdong, Huang, Zhiguang, Zou, Minji, Fu, Wenliang, Xing, Weiwei, Xu, Donggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412419/
https://www.ncbi.nlm.nih.gov/pubmed/28422048
http://dx.doi.org/10.3390/ijms18040835