Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction

Cardiac dysfunction, in particular of the left ventricle, is a common and early event in sepsis, and is strongly associated with an increase in patients’ mortality. Acid sphingomyelinase (SMPD1)—the principal regulator for rapid and transient generation of the lipid mediator ceramide—is involved in...

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Detalles Bibliográficos
Autores principales: Chung, Ha-Yeun, Kollmey, Anna S., Schrepper, Andrea, Kohl, Matthias, Bläss, Markus F., Stehr, Sebastian N., Lupp, Amelie, Gräler, Markus H., Claus, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412423/
https://www.ncbi.nlm.nih.gov/pubmed/28420138
http://dx.doi.org/10.3390/ijms18040839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412423/
https://www.ncbi.nlm.nih.gov/pubmed/28420138
http://dx.doi.org/10.3390/ijms18040839

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