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Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells

Retinoids may regulate cell differentiation as ligands of retinoic acid receptors (RARs) and/or retinoid X receptors (RXRs). We showed that RAR agonists promoted adipogenesis by upregulating the expression of CCAAT/enhancer-binding protein β (C/EBPβ) in the early stages, but blocked adipogenesis at...

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Detalles Bibliográficos
Autores principales: Cao, Jun, Ma, Yuhong, Yao, Weiqi, Zhang, Xiaoye, Wu, Dongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412426/
https://www.ncbi.nlm.nih.gov/pubmed/28420144
http://dx.doi.org/10.3390/ijms18040842