Cargando…
Fisetin Protects PC12 Cells from Tunicamycin-Mediated Cell Death via Reactive Oxygen Species Scavenging and Modulation of Nrf2-Driven Gene Expression, SIRT1 and MAPK Signaling in PC12 Cells
Background: Fisetin (3,7,3′,4′-tetrahydroxyflavone) is a dietary flavonol and exhibits antioxidant, anti-inflammatory, and neuroprotective activities. However, high concentration of fisetin is reported to produce reactive oxygen species (ROS), induce endoplasmic reticulum (ER) stress and cause cytot...
Autores principales: | Yen, Jui-Hung, Wu, Pei-Shan, Chen, Shu-Fen, Wu, Ming-Jiuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412436/ https://www.ncbi.nlm.nih.gov/pubmed/28420170 http://dx.doi.org/10.3390/ijms18040852 |
Ejemplares similares
-
Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells
por: Wu, Pei-Shan, et al.
Publicado: (2015) -
The Neuroprotective Effects of Flavonoid Fisetin against Corticosterone-Induced Cell Death through Modulation of ERK, p38, and PI3K/Akt/FOXO3a-Dependent Pathways in PC12 Cells
por: Chang, Pei-Rong, et al.
Publicado: (2023) -
Luteolin Induces microRNA-132 Expression and Modulates Neurite Outgrowth in PC12 Cells
por: Lin, Lian-Fang, et al.
Publicado: (2012) -
Luteolin Modulates 6-Hydroxydopamine-Induced Transcriptional Changes of Stress Response Pathways in PC12 Cells
por: Hu, Ling-Wei, et al.
Publicado: (2014) -
Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells
por: Noordman, Yvet E, et al.
Publicado: (2006)