Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice

High incidence rate of Alzheimer’s disease (AD) is observed in patients with type 2 diabetes. Aggregated β-amyloid (Aβ) and hyperphosphorylated tau are the hallmarks of AD. Hyperphosphorylated tau has been detected in diabetic animals as well as in diabetic patients. Folates mediate the transfer of...

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Detalles Bibliográficos
Autores principales: Zheng, Miaoyan, Zou, Chen, Li, Mengyue, Huang, Guowei, Gao, Yuxia, Liu, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412442/
https://www.ncbi.nlm.nih.gov/pubmed/28422052
http://dx.doi.org/10.3390/ijms18040861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412442/
https://www.ncbi.nlm.nih.gov/pubmed/28422052
http://dx.doi.org/10.3390/ijms18040861

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