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Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice
High incidence rate of Alzheimer’s disease (AD) is observed in patients with type 2 diabetes. Aggregated β-amyloid (Aβ) and hyperphosphorylated tau are the hallmarks of AD. Hyperphosphorylated tau has been detected in diabetic animals as well as in diabetic patients. Folates mediate the transfer of...
Autores principales: | Zheng, Miaoyan, Zou, Chen, Li, Mengyue, Huang, Guowei, Gao, Yuxia, Liu, Huan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412442/ https://www.ncbi.nlm.nih.gov/pubmed/28422052 http://dx.doi.org/10.3390/ijms18040861 |
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