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Control of Kir channel gating by cytoplasmic domain interface interactions
Inward rectifier potassium (Kir) channels are expressed in almost all mammalian tissues and play critical roles in the control of excitability. Pancreatic ATP-sensitive K (K(ATP)) channels are key regulators of insulin secretion and comprise Kir6.2 subunits coupled to sulfonylurea receptors. Because...
Autores principales: | Borschel, William F., Wang, Shizhen, Lee, Sunjoo, Nichols, Colin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412532/ https://www.ncbi.nlm.nih.gov/pubmed/28389584 http://dx.doi.org/10.1085/jgp.201611719 |
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