The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy

Autophagy-dependent clearance of ubiquitinated and aggregated proteins is critical to protein quality control, but the underlying mechanisms are not well understood. Here, we report the essential role of the BEACH (beige and Chediak–Higashi) and WD40 repeat-containing protein WDR81 in eliminating ub...

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Detalles Bibliográficos
Autores principales: Liu, Xuezhao, Li, Yang, Wang, Xin, Xing, Ruxiao, Liu, Kai, Gan, Qiwen, Tang, Changyong, Gao, Zhiyang, Jian, Youli, Luo, Shouqing, Guo, Weixiang, Yang, Chonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412561/
https://www.ncbi.nlm.nih.gov/pubmed/28404643
http://dx.doi.org/10.1083/jcb.201608039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412561/
https://www.ncbi.nlm.nih.gov/pubmed/28404643
http://dx.doi.org/10.1083/jcb.201608039

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