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Preprotein mature domains contain translocase targeting signals that are essential for secretion

Secretory proteins are only temporary cytoplasmic residents. They are typically synthesized as preproteins, carrying signal peptides N-terminally fused to their mature domains. In bacteria secretion largely occurs posttranslationally through the membrane-embedded SecA-SecYEG translocase. Upon crossi...

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Detalles Bibliográficos
Autores principales: Chatzi, Katerina E., Sardis, Marios Frantzeskos, Tsirigotaki, Alexandra, Koukaki, Marina, Šoštarić, Nikolina, Konijnenberg, Albert, Sobott, Frank, Kalodimos, Charalampos G., Karamanou, Spyridoula, Economou, Anastassios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412566/
https://www.ncbi.nlm.nih.gov/pubmed/28404644
http://dx.doi.org/10.1083/jcb.201609022