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Long-Lasting Impairment of mGluR(5)-Activated Intracellular Pathways in the Striatum After Withdrawal of Cocaine Self-Administration

BACKGROUND: Cocaine addiction continues to be a major heath concern, and despite public health intervention there is a lack of efficient pharmacological treatment options. A newly identified potential target are the group I metabotropic glutamate receptors, with allosteric modulators showing particu...

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Detalles Bibliográficos
Autores principales: Hoffmann, Hanne Mette, Crouzin, Nadine, Moreno, Estefanía, Raivio, Noora, Fuentes, Silvia, McCormick, Peter J., Ortiz, Jordi, Vignes, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412585/
https://www.ncbi.nlm.nih.gov/pubmed/27744406
http://dx.doi.org/10.1093/ijnp/pyw086