Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression

C1q collagen-like region (CLR) engaging and activating the LAIR-1 inhibitory immunoreceptor represents a non-complement mechanism for maintaining immune quiescence. Given the binding promiscuity of C1q’s globular region (gC1q), we hypothesized that C1q concurrently associates with distinct inhibitor...

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Detalles Bibliográficos
Autores principales: Son, Myoungsun, Diamond, Betty, Volpe, Bruce T., Aranow, Cynthia B., Mackay, Meggan C., Santiago-Schwarz, Frances
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412647/
https://www.ncbi.nlm.nih.gov/pubmed/28325905
http://dx.doi.org/10.1038/s41598-017-00290-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412647/
https://www.ncbi.nlm.nih.gov/pubmed/28325905
http://dx.doi.org/10.1038/s41598-017-00290-w

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