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Reduced local input to fast‐spiking interneurons in the somatosensory cortex in the GABA(A) γ2 R43Q mouse model of absence epilepsy

OBJECTIVE: Absence seizures in childhood absence epilepsy are initiated in the thalamocortical (TC) system. We investigated if these seizures result from altered development of the TC system before the appearance of seizures in mice containing a point mutation in γ‐aminobutyric acid A (GABA(A)) rece...

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Detalles Bibliográficos
Autores principales: Currie, Stephen P., Luz, Liliana L., Booker, Sam A., Wyllie, David J. A., Kind, Peter C., Daw, Michael I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412680/
https://www.ncbi.nlm.nih.gov/pubmed/28195311
http://dx.doi.org/10.1111/epi.13693