Cargando…

Reduced local input to fast‐spiking interneurons in the somatosensory cortex in the GABA(A) γ2 R43Q mouse model of absence epilepsy

OBJECTIVE: Absence seizures in childhood absence epilepsy are initiated in the thalamocortical (TC) system. We investigated if these seizures result from altered development of the TC system before the appearance of seizures in mice containing a point mutation in γ‐aminobutyric acid A (GABA(A)) rece...

Descripción completa

Detalles Bibliográficos
Autores principales:	Currie, Stephen P., Luz, Liliana L., Booker, Sam A., Wyllie, David J. A., Kind, Peter C., Daw, Michael I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Full‐length Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412680/ https://www.ncbi.nlm.nih.gov/pubmed/28195311 http://dx.doi.org/10.1111/epi.13693

Ejemplares similares

Altered GABA(A) Receptor Expression in the Primary Somatosensory Cortex of a Mouse Model of Genetic Absence Epilepsy
por: Hassan, Muhammad, et al.
Publicado: (2022)

Gap Junctions Link Regular-Spiking and Fast-Spiking Interneurons in Layer 5 Somatosensory Cortex
por: Hatch, Robert J., et al.
Publicado: (2017)

Cell-type-specific recruitment of GABAergic interneurons in the primary somatosensory cortex by long-range inputs
por: Naskar, Shovan, et al.
Publicado: (2021)

Contribution of NMDA Receptors to Synaptic Function in Rat Hippocampal Interneurons
por: Booker, Sam A., et al.
Publicado: (2021)

Fast-Spiking Interneurons Exposed in Tumor-Associated Epilepsy
por: Maguire, Jamie
Publicado: (2019)

Hippocampal Expression of Connexin36 and Connexin43 during Epileptogenesis in Pilocarpine Model of Epilepsy
por: Motaghi, Sahel, et al.
Publicado: (2017)

An automated, machine learning–based detection algorithm for spike‐wave discharges (SWDs) in a mouse model of absence epilepsy
por: Pfammatter, Jesse A., et al.
Publicado: (2019)

Hilar Somatostatin Interneurons Contribute to Synchronized GABA Activity in an In Vitro Epilepsy Model
por: Grosser, Sabine, et al.
Publicado: (2014)

Fluctuating Inhibitory Inputs Promote Reliable Spiking at Theta Frequencies in Hippocampal Interneurons
por: Sritharan, Duluxan, et al.
Publicado: (2012)

Enhanced tonic GABA(A) inhibition in typical absence epilepsy
por: Cope, David W., et al.
Publicado: (2009)

T76. INVESTIGATION OF NAV1.1 POSITIVE MODULATOR EFFECTS ON FAST SPIKING INTERNEURONS IN SOMATOSENSORY CORTEX SLICES
por: Ildiko, Piszar, et al.
Publicado: (2018)

Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A )receptor chloride channels
por: Ying, Shui-Wang, et al.
Publicado: (2005)

Presynaptic GABA(B) receptors functionally uncouple somatostatin interneurons from the active hippocampal network
por: Booker, Sam A, et al.
Publicado: (2020)

Developmental Inhibitory Changes in the Primary Somatosensory Cortex of the Stargazer Mouse Model of Absence Epilepsy
por: Hassan, Muhammad, et al.
Publicado: (2023)

Desynchronization of Neocortical Networks by Asynchronous Release of GABA at Autaptic and Synaptic Contacts from Fast-Spiking Interneurons
por: Manseau, Frédéric, et al.
Publicado: (2010)

Childhood Absence Epilepsy Associated With Concomitant Centrotemporal Spikes
por: Jocic-Jakubi, Bosanka, et al.
Publicado: (2022)

Timing matters: Impact of anticonvulsant drug treatment and spikes on seizure risk in benign epilepsy with centrotemporal spikes
por: Xie, Wenting, et al.
Publicado: (2018)

Inhibitory inputs to an inhibitory interneuron: Spontaneous postsynaptic currents and GABA(A) receptors of A17 amacrine cells in the rat retina
por: Beltrán‐Matas, Pablo, et al.
Publicado: (2022)

Augmentation of Tonic GABA(A) Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABA(A) Receptors
por: Errington, Adam C., et al.
Publicado: (2011)

Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes
por: Verhoeven, Thibault, et al.
Publicado: (2017)

Memory Functioning in Children with Epilepsy: Frontal Lobe Epilepsy, Childhood Absence Epilepsy, and Benign Epilepsy with Centrotemporal Spikes
por: Lopes, Ana Filipa, et al.
Publicado: (2014)

Current Controversy: Spikes, Bursts, and Synchrony in Generalized Absence Epilepsy: Unresolved Questions Regarding Thalamocortical Synchrony in Absence Epilepsy
por: Huguenard, John
Publicado: (2019)

Optogenetic stimulation reveals distinct modulatory properties of thalamostriatal vs corticostriatal glutamatergic inputs to fast-spiking interneurons
por: Sciamanna, Giuseppe, et al.
Publicado: (2015)

Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy
por: Tewari, Bhanu P., et al.
Publicado: (2018)

Morphology, physiology and synaptic connectivity of local interneurons in the mouse somatosensory thalamus
por: Simko, Jane, et al.
Publicado: (2021)

Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy
por: Upadhya, Dinesh, et al.
Publicado: (2022)

Integrating Non-spiking Interneurons in Spiking Neural Networks
por: Strohmer, Beck, et al.
Publicado: (2021)

Morning/Evening Differences in Somatosensory Inputs for Postural Control
por: Bougard, Clément, et al.
Publicado: (2014)

The influence of afferent input on somatosensory suppression during grasping
por: Broda, Maximilian Davide, et al.
Publicado: (2020)

Decreased functional connectivity within a language subnetwork in benign epilepsy with centrotemporal spikes
por: McGinnity, Colm J., et al.
Publicado: (2017)

Synaptic Changes in AMPA Receptor Subunit Expression in Cortical Parvalbumin Interneurons in the Stargazer Model of Absence Epilepsy
por: Adotevi, Nadia K., et al.
Publicado: (2017)

Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy
por: Ferguson, Brielle, et al.
Publicado: (2023)

Scanned optogenetic control of mammalian somatosensory input to map input-specific behavioral outputs
por: Schorscher-Petcu, Ara, et al.
Publicado: (2021)

A study on spike focus dependence of high‐frequency activity in idiopathic focal epilepsy in childhood
por: Shibata, Takashi, et al.
Publicado: (2016)

Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study
por: Wu, Joyce Y., et al.
Publicado: (2019)

TDP-43 accelerates age-dependent degeneration of interneurons
por: Tsuiji, Hitomi, et al.
Publicado: (2017)

Hypocretin (Orexin) Regulates Glutamate Input to Fast-Spiking Interneurons in Layer V of the Fr2 Region of the Murine Prefrontal Cortex
por: Aracri, Patrizia, et al.
Publicado: (2015)

Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix
por: Hayani, Hussam, et al.
Publicado: (2018)

Modulation of cortical vestibular processing by somatosensory inputs in the posterior insula
por: Hashimoto, Teruo, et al.
Publicado: (2013)

Sensory input is required for callosal axon targeting in the somatosensory cortex
por: Huang, Ying, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_sgo082o75ppjf589rjv87m6b8p