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Seeding and transgenic overexpression of alpha‐synuclein triggers dendritic spine pathology in the neocortex
Although misfolded and aggregated α‐synuclein (α‐syn) is recognized in the disease progression of synucleinopathies, its role in the impairment of cortical circuitries and synaptic plasticity remains incompletely understood. We investigated how α‐synuclein accumulation affects synaptic plasticity in...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412764/ https://www.ncbi.nlm.nih.gov/pubmed/28351932 http://dx.doi.org/10.15252/emmm.201607305 |