Antibodies inhibit transmission and aggregation of C9orf72 poly‐GA dipeptide repeat proteins

Cell‐to‐cell transmission of protein aggregates is an emerging theme in neurodegenerative disease. Here, we analyze the dipeptide repeat (DPR) proteins that form neuronal inclusions in patients with hexanucleotide repeat expansion C9orf72, the most common known cause of amyotrophic lateral sclerosis...

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Detalles Bibliográficos
Autores principales: Zhou, Qihui, Lehmer, Carina, Michaelsen, Meike, Mori, Kohji, Alterauge, Dominik, Baumjohann, Dirk, Schludi, Martin H, Greiling, Johanna, Farny, Daniel, Flatley, Andrew, Feederle, Regina, May, Stephanie, Schreiber, Franziska, Arzberger, Thomas, Kuhm, Christoph, Klopstock, Thomas, Hermann, Andreas, Haass, Christian, Edbauer, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412769/
https://www.ncbi.nlm.nih.gov/pubmed/28351931
http://dx.doi.org/10.15252/emmm.201607054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412769/
https://www.ncbi.nlm.nih.gov/pubmed/28351931
http://dx.doi.org/10.15252/emmm.201607054

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