USP26 regulates TGF‐β signaling by deubiquitinating and stabilizing SMAD7

The amplitude of transforming growth factor‐β (TGF‐β) signal is tightly regulated to ensure appropriate physiological responses. As part of negative feedback loop SMAD7, a direct transcriptional target of downstream TGF‐β signaling acts as a scaffold to recruit the E3 ligase SMURF2 to target the TGF...

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Detalles Bibliográficos
Autores principales: Kit Leng Lui, Sarah, Iyengar, Prasanna Vasudevan, Jaynes, Patrick, Isa, Zul Fazreen Bin Adam, Pang, Brendan, Tan, Tuan Zea, Eichhorn, Pieter Johan Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412796/
https://www.ncbi.nlm.nih.gov/pubmed/28381482
http://dx.doi.org/10.15252/embr.201643270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412796/
https://www.ncbi.nlm.nih.gov/pubmed/28381482
http://dx.doi.org/10.15252/embr.201643270

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