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Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1‐13C]pyruvate

PURPOSE: To demonstrate the feasibility of mapping intracellular pH within the in vivo rodent heart. Alterations in cardiac acid‐base balance can lead to acute contractile depression and alterations in Ca(2+) signaling. The transient reduction in adenosine triphosphate (ATP) consumption and cardiac...

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Detalles Bibliográficos
Autores principales: Lau, Angus Z., Miller, Jack J., Tyler, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412837/
https://www.ncbi.nlm.nih.gov/pubmed/27173806
http://dx.doi.org/10.1002/mrm.26260