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Cefiderocol, a Siderophore Cephalosporin for Gram‐Negative Bacterial Infections: Pharmacokinetics and Safety in Subjects With Renal Impairment

Cefiderocol, a new injectable siderophore cephalosporin antibiotic, has promising in vitro and in vivo activity against Gram‐negative bacteria including multidrug‐resistant Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. Cefiderocol is mainly renally eliminated. The pharm...

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Detalles Bibliográficos
Autores principales: Katsube, Takayuki, Echols, Roger, Arjona Ferreira, Juan Camilo, Krenz, Heidi K., Berg, Jolene Kay, Galloway, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412848/
https://www.ncbi.nlm.nih.gov/pubmed/27874971
http://dx.doi.org/10.1002/jcph.841