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TORC1 coordinates the conversion of Sic1 from a target to an inhibitor of cyclin-CDK-Cks1

Eukaryotic cell cycle progression through G(1)–S is driven by hormonal and growth-related signals that are transmitted by the target of rapamycin complex 1 (TORC1) pathway. In yeast, inactivation of TORC1 restricts G(1)–S transition due to the rapid clearance of G(1) cyclins (Cln) and the stabilizat...

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Detalles Bibliográficos
Autores principales: Moreno-Torres, Marta, Jaquenoud, Malika, Péli-Gulli, Marie-Pierre, Nicastro, Raffaele, De Virgilio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412858/
https://www.ncbi.nlm.nih.gov/pubmed/28496991
http://dx.doi.org/10.1038/celldisc.2017.12